Uveal Melanoma Outcome Predictor
BCVA (LogMAR) Explained
BCVA (Best-Corrected Visual Acuity) measures the sharpest vision achievable with corrective lenses. It is expressed here on the LogMAR scale (logarithm of the minimum angle of resolution).
- 0.0 = normal vision (Snellen 20/20)
- Negative values (e.g. -0.3) = better than normal
- Higher positive values = worse vision
- 1.0 = legal blindness threshold (Snellen 20/200)
- 2.0+ = very low vision (counting fingers, hand motion, light perception)
Each 0.1 increase in LogMAR represents a halving of the visual angle resolved. The Snellen equivalent is shown in parentheses in the dropdown for convenience.
Abbreviations: CF = Counting Fingers, HM = Hand Motion, LP = Light Perception, NLP = No Light Perception.
Tumor Volume Calculation
We approximate the uveal melanoma as an ellipsoid (or ellipsoid-like shape) to estimate tumor volume. In practice, we use the following formula:
Where:
- z = apex (thickness) in millimeters
- x = maximum diameter in the x-axis (mm)
- y = maximum diameter in the y-axis (mm)
- π ≈ 3.14159
Our script multiplies these terms as shown above to yield an estimation of the tumor size in cubic millimeters.
AJCC Classification (T Category)
This table summarizes the AJCC T Category classification for choroidal and ciliary body melanoma, based on the tumor's thickness (mm) and largest basal diameter (mm). Our tool automatically assigns a stage (T1–T4) based on these measurements.
| Thickness (mm) | Largest Basal Diameter (mm) | ||||||
|---|---|---|---|---|---|---|---|
| ≤3.0 | 3.1–6.0 | 6.1–9.0 | 9.1–12.0 | 12.1–15.0 | 15.1–18.0 | >18.0 | |
| >15.0 | 4 | 4 | 4 | 4 | 4 | 4 | 4 |
| 12.1–15.0 | 3 | 3 | 3 | 3 | 3 | 4 | 4 |
| 9.1–12.0 | 3 | 3 | 3 | 3 | 3 | 3 | 4 |
| 6.1–9.0 | 2 | 2 | 2 | 2 | 3 | 3 | 4 |
| 3.1–6.0 | 1 | 1 | 1 | 2 | 2 | 3 | 4 |
| ≤3.0 | 1 | 1 | 1 | 1 | 2 | 2 | 4 |
Adapted from the AJCC Cancer Staging Manual, 8th ed. Amin MB, Edge SB, Greene FL, et al., eds. New York: Springer; 2017.
doi:10.1007/978-3-319-40618-3
